Prof. Dr. Eveline Lescrinier

contact

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research projects

• Synthesis and characterisation of backbone modified mRNA [more...]
• Optimization of self-amplifying RNA and mRNA production and formulation through advanced microfluidics. [more...]
• MORPHO-ViBe. Developping a new probe harboring vibrational Stark effect spectroscopic sensitivity and targeting the catalytic pocket of the ribosome [more...]
• Optimization of self-amplifying RNA and mRNA production and formulation through advanced microfluidics (saRplix) [more...]
• Exploring Novel Synergies Between Antiviral Nucleotides and Small Molecule Immunomodulators for Hepatitis B virus (HBV) Treatment [more...]
• Development of alkyl-PMO based antibiotics [more...]
• Developing XNA aptamer selection tools for the advancement of aptamer diagnostic and therapeutic applications [more...]
• Development of broad spectrum antibiotics with a new mode of action through establishing new tools for optimal sequence selection in vitro and in silico design of antisense oligonucleotides. [more...]
• Stereocontrolled synthesis and characterization of novel sugar-phosphate modified nucleotides [more...]
• Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology. [more...]

recent publications

• Chen, Z., Lescrinier, E. (sup.), De Jonghe, S. (cosup.), Groaz, E. (cosup.) (2026). Synthesis of C-nucleoside analogues as therapeutic agents.
• Bulai, R-G., Parolini, M., Cummins, K.A., Purnal, S., Lescrinier, E., Rozenski, J., Masschelein, J., Verwilst, P. (corresp. author) (2026). Polarity-Driven Scaffold Optimization of Diaryl Ether FabV Inhibitors to Enhance Aqueous Solubility. Chemmedchem, 21 (19), Art.No. e70512. doi: 10.1002/cmdc.70512
• Chen, Z., Groaz, E., Rozenski, J., De Jonghe, S., Lescrinier, E. (corresp. author) (2026). Synthesis and Antiviral Evaluation of Sugar-Modified Pseudouridine Analogs. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 29 (37). doi: 10.1002/ejoc.70799
• Chaillou, S., Bernardes Pinheiro, V. (sup.), Herdewyn, P. (cosup.), Lescrinier, E. (cosup.) (2026). Defining, analyzing, and engineering functional nucleic acid systems.
• El Arnouki Belhaji, F., De Ruysscher, D., Vanreppelen, G., Huybrechts, L-L., Alanjary, M.M., Zdouc, M.M., de los Santos, E.L C., Demaerel, J., Vaneeckhaute, E., Van Goethem, O., Gerstmans, H., Breynaert, E., Van Dijck, P., Medema, M.H., Weir, A.N M., Lescrinier, E., Masschelein, J. (corresp. author) (2026). Charting the Biosynthetic Landscape of Hybrid Polyketide-Nonribosomal Peptide-Specialized Lipids. JACS Au, 6 (6), 3363-3375. doi: 10.1021/jacsau.6c00386
• Chaillou, S. (joint first author), Thonon, S. (joint first author), Reynders, S., Lescrinier, E., Pinheiro, V.B. (corresp. author) (2026). Are we there yet with XNA aptamers? RSC ADVANCES, 16 (24), 22227-22246. doi: 10.1039/d5ra05395a
• Derden, M., Lescrinier, E. (sup.), Groaz, E. (cosup.) (2026). Stereocontrolled synthesis and characterization of novel sugar-phosphate modified nucleotides.
• Lelong, J., Lescrinier, E. (contr.) (2025). China maakt als tweede grootste medicijnenproducent ook alsmaar meer innovatieve medicatie. De Morgen.
• Lescrinier, E. (contr.) (2025). Opmars van chinese bedrijven zet belgische farmasector onder druk. Het Laatste Nieuws.
• Tu, L., Horak, J. (corresp. author), Krentz, D., Zwicklbauer, K., Hartmann, K., Lescrinier, E., Alberer, M., von Both, U., Koletzko, B. (corresp. author) (2025). Structure elucidation and quantification of the active pharmaceutical ingredient in a non-approved drug and in cat serum using QTRAP-MS/MS and ZenoTOF-MS/MS. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 265, Art.No. ARTN 116995. doi: 10.1016/j.jpba.2025.116995

For a complete list of publications, see lirias database or PubMed.